To evaluate the biocompatibility of the Indian Portland cement with potential for use in dentistry: An animal study

This study evaluated the biocompatibility of the Indian Portland cement with potential for use in dentistry. This study was performed in Swiss albino mice, by implanting the Indian Portland cement pellets subcutaneously. After 1, 3, and 6 weeks the tissue specimens were prepared for histological examination. The histological analysis showed moderate to severe inflammation at 1 week. The inflammation gradually decreased by 6 weeks, with most of the specimens showing the absence of inflammatory reaction. According to these experimental conditions, the tested Indian Portland cement was biocompatible.