Association between serum soluble corin and hyperglycaemia: a cross-sectional study among Chinese adults

ObjectivesDecreased natriuretic peptides are risk factors for diabetes. As a physiological activator of natriuretic peptides, corin may play a role in glucose metabolism. Here, we aimed to test the hypothesis in a general population of China.DesignCross-sectional study.SettingA population study in S...

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Veröffentlicht in:BMJ open 2015-12, Vol.5 (12), p.e009085-e009085
Hauptverfasser: Liu, Yan, Peng, Hao, Zhang, Qiu, Zhang, Peipei, Tian, Yunfan, Chao, Xiangqin, Zhang, Yonghong
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Sprache:eng
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Zusammenfassung:ObjectivesDecreased natriuretic peptides are risk factors for diabetes. As a physiological activator of natriuretic peptides, corin may play a role in glucose metabolism. Here, we aimed to test the hypothesis in a general population of China.DesignCross-sectional study.SettingA population study in Suzhou, China.ParticipantsA total of 2498 participants aged above 30 years were included in the study.Outcome measuresThe association between serum soluble corin and hyperglycaemia was examined in men and women, using non-conditional logistic regression models, respectively.ResultsSerum soluble corin, in men and women, was significantly higher in participants with hyperglycaemia than in those without (all p
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2015-009085