From Hype to Hope: The Gut Microbiota in Enteric Infectious Disease

One of the clearest functions of the gut microbiota in humans is resistance to colonization by enteric bacterial pathogens. Reconstitution of the microbiota offers an exciting therapeutic approach, but great challenges must be overcome. The gut microbiota in humans confers resistance to colonization...

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Veröffentlicht in:	Cell 2015-12, Vol.163 (6), p.1326-1332
Hauptverfasser:	McKenney, Peter T., Pamer, Eric G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiosis Bacteroidetes - classification Bacteroidetes - metabolism Communicable Diseases - microbiology Communicable Diseases - therapy Firmicutes - classification Firmicutes - metabolism Gastrointestinal Diseases - microbiology Gastrointestinal Diseases - therapy Gastrointestinal Microbiome Humans Immunomodulation
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Beschreibung
Zusammenfassung:	One of the clearest functions of the gut microbiota in humans is resistance to colonization by enteric bacterial pathogens. Reconstitution of the microbiota offers an exciting therapeutic approach, but great challenges must be overcome. The gut microbiota in humans confers resistance to colonization by enteric bacterial pathogens, and reconstitution of the microbiota presents exciting therapeutic opportunities
ISSN:	0092-8674 1097-4172
DOI:	10.1016/j.cell.2015.11.032