Management of latent Mycobacterium tuberculosis infection: WHO guidelines for low tuberculosis burden countries

Latent tuberculosis infection (LTBI) is characterised by the presence of immune responses to previously acquired Mycobacterium tuberculosis infection without clinical evidence of active tuberculosis (TB). Here we report evidence-based guidelines from the World Health Organization for a public health...

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Veröffentlicht in:The European respiratory journal 2015-12, Vol.46 (6), p.1563-1576
Hauptverfasser: Getahun, Haileyesus, Matteelli, Alberto, Abubakar, Ibrahim, Aziz, Mohamed Abdel, Baddeley, Annabel, Barreira, Draurio, Den Boon, Saskia, Borroto Gutierrez, Susana Marta, Bruchfeld, Judith, Burhan, Erlina, Cavalcante, Solange, Cedillos, Rolando, Chaisson, Richard, Chee, Cynthia Bin-Eng, Chesire, Lucy, Corbett, Elizabeth, Dara, Masoud, Denholm, Justin, de Vries, Gerard, Falzon, Dennis, Ford, Nathan, Gale-Rowe, Margaret, Gilpin, Chris, Girardi, Enrico, Go, Un-Yeong, Govindasamy, Darshini, D Grant, Alison, Grzemska, Malgorzata, Harris, Ross, Horsburgh, Jr, C Robert, Ismayilov, Asker, Jaramillo, Ernesto, Kik, Sandra, Kranzer, Katharina, Lienhardt, Christian, LoBue, Philip, Lönnroth, Knut, Marks, Guy, Menzies, Dick, Migliori, Giovanni Battista, Mosca, Davide, Mukadi, Ya Diul, Mwinga, Alwyn, Nelson, Lisa, Nishikiori, Nobuyuki, Oordt-Speets, Anouk, Rangaka, Molebogeng Xheedha, Reis, Andreas, Rotz, Lisa, Sandgren, Andreas, Sañé Schepisi, Monica, Schünemann, Holger J, Sharma, Surender Kumar, Sotgiu, Giovanni, Stagg, Helen R, Sterling, Timothy R, Tayeb, Tamara, Uplekar, Mukund, van der Werf, Marieke J, Vandevelde, Wim, van Kessel, Femke, van't Hoog, Anna, Varma, Jay K, Vezhnina, Natalia, Voniatis, Constantia, Vonk Noordegraaf-Schouten, Marije, Weil, Diana, Weyer, Karin, Wilkinson, Robert John, Yoshiyama, Takashi, Zellweger, Jean Pierre, Raviglione, Mario
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Sprache:eng
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Zusammenfassung:Latent tuberculosis infection (LTBI) is characterised by the presence of immune responses to previously acquired Mycobacterium tuberculosis infection without clinical evidence of active tuberculosis (TB). Here we report evidence-based guidelines from the World Health Organization for a public health approach to the management of LTBI in high risk individuals in countries with high or middle upper income and TB incidence of
ISSN:0903-1936
1399-3003
DOI:10.1183/13993003.01245-2015