Prevention and therapy of fungal infection in severe acute pancreatitis: A prospective clinical study

To investigate the prevention and therapy of fungal infection in patients with severe acute pancreatitis (SAP). Seventy patients with SAP admitted from Jan. 1998 to Dec. 2002 were randomly divided into garlicin prevention group, fluconazole (low dosage) prevention group and control group. The incide...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2003-11, Vol.9 (11), p.2619-2621
Hauptverfasser:	He, Yue-Ming, Lv, Xin-Sheng, Ai, Zhong-Li, Liu, Zhi-Su, Qian, Qun, Sun, Quan, Chen, Ji-Wei, Lei, Dao-Xiong, Jiang, Cong-Qing, Yuan, Yu-Fong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Aged Allyl Compounds - administration & dosage Amphotericin B - administration & dosage Antifungal Agents - administration & dosage Brief Reports Disulfides - administration & dosage Female Fluconazole - administration & dosage Humans Incidence Male Middle Aged Mycoses - drug therapy Mycoses - mortality Mycoses - prevention & control Pancreatitis - microbiology Pancreatitis - mortality Prospective Studies Treatment Outcome
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Zusammenfassung:	To investigate the prevention and therapy of fungal infection in patients with severe acute pancreatitis (SAP). Seventy patients with SAP admitted from Jan. 1998 to Dec. 2002 were randomly divided into garlicin prevention group, fluconazole (low dosage) prevention group and control group. The incidence of fungal infection, the fungal clearance and mortality after treatment were compared. The incidence of fungal infection in garlicin group and fluconazole group was lower than that in control group (16% vs 30%, P
ISSN:	1007-9327 2219-2840
DOI:	10.3748/wjg.v9.i11.2619