Effect of Maotai liquor in inducing metallothioneins and on hepatic stellate cells

AIM:To explore the possible mechanism why drinking Maotai liquor dose not cause hepatic fibrosis.METHODS:After being fed with Maotai for 56 days consecutively,the male SDrats were decollated for detecting the biological indexes,and the livers were harvested to examine the liver indexes and the level...

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Veröffentlicht in:World journal of gastroenterology : WJG 2002-06, Vol.8 (3), p.520-523
Hauptverfasser: Cheng, Ming-Liang, Wu, Jun, Wang, Hai-Qin, Xue, Lie-Ming, Tan, Ying-Zhi, Ping, Liu, Li, Cheng-Xiu, Huang, Neng-Hui, Yao, Yu-Mei, Ren, Lan-Zheng, Ye, Lan, Li, Ling, Jia, Mei-Lin
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Sprache:eng
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Zusammenfassung:AIM:To explore the possible mechanism why drinking Maotai liquor dose not cause hepatic fibrosis.METHODS:After being fed with Maotai for 56 days consecutively,the male SDrats were decollated for detecting the biological indexes,and the livers were harvested to examine the liver indexes and the level of hepatic metallothioneins(MT),Hepatic stellate cells(HSC) proliferation and collagen generation were also observed.RESULTS:Hepatic MT contents were 216.0ng.g^-1±108ng.g^-1 in the rats of Maotai group and 10.0ng.g^-1±2.8ng.g^-1 in the normal control group,which was increased obviously in Maotain group(P
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v8.i3.520