Identification and evaluation of vaccine candidate antigens from the poultry red mite (Dermanyssus gallinae)

[Display omitted] •Ten poultry red mite vaccine candidate antigens were identified and recombinant versions produced.•Mite mortality was monitored after feeding on the blood from vaccinated hens.•A ⩾1.6-fold increased risk of mite death was observed with four of the vaccine candidates (P

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Bibliographische Detailangaben
Veröffentlicht in:	International journal for parasitology 2015-11, Vol.45 (13), p.819-830
Hauptverfasser:	Bartley, Kathryn, Wright, Harry W., Huntley, John F., Manson, Erin D.T., Inglis, Neil F., McLean, Kevin, Nath, Mintu, Bartley, Yvonne, Nisbet, Alasdair J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - chemistry Antibodies - immunology Antibody Formation Antigens - immunology Antigens - isolation & purification Chickens Dermanyssus gallinae Female Hemelipoglycoprotein Immunoglobulins - chemistry Immunoglobulins - immunology Mite Infestations - immunology Mite Infestations - parasitology Mite Infestations - prevention & control Mite Infestations - veterinary Mites - drug effects Mites - immunology Poultry Poultry Diseases - immunology Poultry Diseases - parasitology Poultry Diseases - prevention & control Proteomics Random Allocation Recombinant Proteins - genetics Serpin Serpins - pharmacology Vaccination - veterinary Vaccine Vaccines - administration & dosage Vaccines - chemistry Vaccines - immunology Vitellogenin Vitellogenins - pharmacology
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Beschreibung
Zusammenfassung:	[Display omitted] •Ten poultry red mite vaccine candidate antigens were identified and recombinant versions produced.•Mite mortality was monitored after feeding on the blood from vaccinated hens.•A ⩾1.6-fold increased risk of mite death was observed with four of the vaccine candidates (P
ISSN:	0020-7519 1879-0135
DOI:	10.1016/j.ijpara.2015.07.004