Reduced rate of knee extensor torque development in older adults with knee osteoarthritis is associated with intrinsic muscle contractile deficits

Reduced rate of knee extensor torque development in older adults with knee osteoarthritis is associated with intrinsic muscle contractile deficits

We examined the effect of knee osteoarthritis on the rate of torque development (RTD) of the knee extensors in older adults with advanced-stage knee osteoarthritis (OA; n=15) and recreationally-active controls (n=15) of similar age, sex and health status, as well as the relationship between RTD and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental gerontology 2015-12, Vol.72, p.16-21
Hauptverfasser: Callahan, Damien M., Tourville, Timothy W., Slauterbeck, James R., Ades, Philip A., Stevens-Lapsley, Jennifer, Beynnon, Bruce D., Toth, Michael J.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Biopsy
Case-Control Studies
Female
Humans
Isometric Contraction - physiology
Knee Joint - physiopathology
Male
Muscle Fibers, Skeletal - pathology
Myosin Heavy Chains - metabolism
Osteoarthritis, Knee - physiopathology
Single muscle fiber
Skinned fiber
Torque
Velocity
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We examined the effect of knee osteoarthritis on the rate of torque development (RTD) of the knee extensors in older adults with advanced-stage knee osteoarthritis (OA; n=15) and recreationally-active controls (n=15) of similar age, sex and health status, as well as the relationship between RTD and the size and contractility of single muscle fibers. OA participants had lower RTD when expressed in absolute terms (Nm/ms). There were sex differences in peak RTD (P
ISSN:0531-5565
1873-6815
DOI:10.1016/j.exger.2015.08.016