Significance of Fas and FasL protein expression in cardiac carcinoma and local lymph node tissues

Significance of Fas and FasL protein expression in cardiac carcinoma and local lymph node tissues

To investigate the relation of Fas and Fas ligand (FasL) protein expression with carcinogenesis and metastasis of cardiac carcinoma. Immunohistochemistry was used to detect Fas and FasL protein expression in 64 cardiac carcinoma tissue samples and 20 normal gastric tissue samples. Relation between F...

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Veröffentlicht in:International journal of clinical and experimental pathology 2015-01, Vol.8 (9), p.11915-11920
Hauptverfasser: Li, Yin, Xu, Da-Fu, Jiang, Dong, Zhao, Jun, Ge, Jin-Feng, Zheng, Shi-Ying
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma - chemistry
Adenocarcinoma - secondary
Adult
Biomarkers, Tumor - analysis
Cardia - chemistry
Cardia - pathology
Case-Control Studies
Cell Differentiation
Chi-Square Distribution
Fas Ligand Protein - analysis
fas Receptor - analysis
Female
Humans
Immunohistochemistry
Lymph Nodes - chemistry
Lymph Nodes - pathology
Lymphatic Metastasis
Male
Middle Aged
Nonlinear Dynamics
Original
Stomach Neoplasms - chemistry
Stomach Neoplasms - pathology
Young Adult
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Zusammenfassung:To investigate the relation of Fas and Fas ligand (FasL) protein expression with carcinogenesis and metastasis of cardiac carcinoma. Immunohistochemistry was used to detect Fas and FasL protein expression in 64 cardiac carcinoma tissue samples and 20 normal gastric tissue samples. Relation between FasL and Fas expression, age and gender of gastric cancer patients, and pathological subtype and lymph node metastasis of gastric cancer was analyzed. The Fas expression level was significantly higher in normal gastric tissue samples than in cardiac carcinoma tissue samples (85.0% vs. 25.0%, P
ISSN:1936-2625