Potential Impact of Prescribing Metformin According to eGFR Rather Than Serum Creatinine

Potential Impact of Prescribing Metformin According to eGFR Rather Than Serum Creatinine

Many societies recommend using estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) to determine metformin eligibility. We examined the potential impact of these recommendations on metformin eligibility among U.S. adults. Metformin eligibility was assessed among 3,902 adult...

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Veröffentlicht in:Diabetes care 2015-11, Vol.38 (11), p.2059-2067
Hauptverfasser: Tuot, Delphine S, Lin, Feng, Shlipak, Michael G, Grubbs, Vanessa, Hsu, Chi-yuan, Yee, Jerry, Shahinian, Vahakn, Saran, Rajiv, Saydah, Sharon, Williams, Desmond E, Powe, Neil R
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Adults
Aged
Aged, 80 and over
Creatinine - blood
Diabetes
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - drug therapy
Diabetes Mellitus, Type 2 - physiopathology
Diabetic Nephropathies - blood
Diabetic Nephropathies - drug therapy
Diabetic Nephropathies - physiopathology
Drug Prescriptions - standards
Epidemiology/Health Services Research
Female
Glomerular Filtration Rate - physiology
Humans
Hypoglycemic Agents - therapeutic use
Impact analysis
Kidneys
Male
Metformin - therapeutic use
Middle Aged
Nutrition Surveys
Practice Guidelines as Topic
Prescription drugs
Renal Insufficiency, Chronic - blood
Young Adult
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Zusammenfassung:Many societies recommend using estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) to determine metformin eligibility. We examined the potential impact of these recommendations on metformin eligibility among U.S. adults. Metformin eligibility was assessed among 3,902 adults with diabetes who participated in the 1999-2010 National Health and Nutrition Examination Surveys and reported routine access to health care, using conventional sCr thresholds (eligible if
ISSN:0149-5992
1935-5548
DOI:10.2337/dc15-0542