In Vitro Evaluation of Achillea Millefolium on the Production and Stimulation of Human Skin Fibroblast Cells (HFS-PI-16)

In Vitro Evaluation of Achillea Millefolium on the Production and Stimulation of Human Skin Fibroblast Cells (HFS-PI-16)

In the present study, we aimed the effects of the hydroalcoholic extract of Achillea millefolium (HEAML) on human skin fibroblast cells (HSF-PI-16) proliferation, stimulation and growth properties. Initially, using HSF-PI-16 monolayer culture, we created one line scratch method as an in vitro wound...

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Veröffentlicht in:Medicinski arhiv 2015-08, Vol.69 (4), p.212-217
Hauptverfasser: Ghobadian, Zahra, Ahmadi, Mohammad Reza Hafezi, Rezazadeh, Leila, Hosseini, Ehsan, Kokhazadeh, Taleb, Ghavam, Samiramis
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Sprache:eng
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Zusammenfassung:In the present study, we aimed the effects of the hydroalcoholic extract of Achillea millefolium (HEAML) on human skin fibroblast cells (HSF-PI-16) proliferation, stimulation and growth properties. Initially, using HSF-PI-16 monolayer culture, we created one line scratch method as an in vitro wound closure and after 3 days monitored via an inverted microscopy. HEAML selectively inhibited proliferation of HSF-PI-16 cells at higher concentration (>20.0 mg/mL), and stimulated at lower concentrations (
ISSN:0350-199X
1986-5961
DOI:10.5455/medarh.2015.69.212-217