Stevens-Johnson syndrome induced by a combination of lamotrigine and valproic acid

Stevens-Johnson syndrome induced by a combination of lamotrigine and valproic acid

Lamotrigine and valproic acid are well-tolerated anticonvulsants, but frequently associated with severe cutaneous reactions, such as the Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis, when used in combination. We report a case of SJS likely induced by the use of a lamotrigine and val...

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Veröffentlicht in:Journal of pharmacy & bioallied science 2015-08, Vol.7 (Suppl 2), p.S756-S758
Hauptverfasser: Kavitha, S, Anbuchelvan, T, Mahalakshmi, V, Sathya, R, Sabarinath, T R, Gururaj, N, Kalaivani, S
Format: Artikel
Sprache:eng
Schlagworte:
Complications and side effects
Dental Science - Case Report
Divalproex
Lamotrigine
Risk factors
Stevens-Johnson syndrome
Valproic acid
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Zusammenfassung:Lamotrigine and valproic acid are well-tolerated anticonvulsants, but frequently associated with severe cutaneous reactions, such as the Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis, when used in combination. We report a case of SJS likely induced by the use of a lamotrigine and valproic acid regimen and as a dental surgeon it is important to identify such lesion and report to pharmacovigilance.
ISSN:0976-4879
0975-7406
0975-7406
DOI:10.4103/0975-7406.163545