Variations in opioid receptor genes in neonatal abstinence syndrome

Highlights • We examine genetic variability in neonatal abstinence syndrome (NAS). • SNPs in opioid receptor and stress response genes are associated with NAS. • Determining key genetic variants will allow us to better predict NAS outcomes.

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Bibliographische Detailangaben
Veröffentlicht in:	Drug and alcohol dependence 2015-10, Vol.155, p.253-259
Hauptverfasser:	Wachman, Elisha M, Hayes, Marie J, Sherva, Richard, Brown, Mark S, Davis, Jonathan M, Farrer, Lindsay A, Nielsen, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Catechol O-Methyltransferase - genetics Female Genetics Humans Infant Infant, Newborn Length of Stay Microarray Analysis Neonatal abstinence syndrome (NAS) Neonatal Abstinence Syndrome - genetics Opioids Polymorphism, Single Nucleotide - genetics Protein Precursors - genetics Psychiatry Receptors, Opioid - genetics Receptors, Opioid, delta - genetics Receptors, Opioid, kappa - genetics Receptors, Opioid, mu - genetics Single nucleotide polymorphisms (SNPs)
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Beschreibung
Zusammenfassung:	Highlights • We examine genetic variability in neonatal abstinence syndrome (NAS). • SNPs in opioid receptor and stress response genes are associated with NAS. • Determining key genetic variants will allow us to better predict NAS outcomes.
ISSN:	0376-8716 1879-0046
DOI:	10.1016/j.drugalcdep.2015.07.001