Analysis of serum IgE reactivity profiles with microarrayed allergens indicates absence of de novo IgE sensitizations in adults
To address the question of whether and how frequently adult allergic patients and nonallergic subjects have IgE sensitizations to new allergen molecules, we performed a retrospective analysis of serum samples using an allergen microarray that contained 85 different purified allergen molecules (ISAC;...
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| Veröffentlicht in: | Journal of allergy and clinical immunology 2012-12, Vol.130 (6), p.1418-1420.e4 |
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| container_end_page | 1420.e4 |
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| container_issue | 6 |
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| container_title | Journal of allergy and clinical immunology |
| container_volume | 130 |
| creator | Lupinek, Christian, MD Marth, Katharina, MD Niederberger, Verena, MD Valenta, Rudolf, MD |
| description | To address the question of whether and how frequently adult allergic patients and nonallergic subjects have IgE sensitizations to new allergen molecules, we performed a retrospective analysis of serum samples using an allergen microarray that contained 85 different purified allergen molecules (ISAC; Phadia, Uppsala, Sweden).2 The 85 allergens on the chip represented 50 allergen families with experimentally confirmed cross-reactivity (see Fig E1 in this article's Online Repository at www.jacionline.org). |
| doi_str_mv | 10.1016/j.jaci.2012.06.028 |
| format | Article |
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| identifier | ISSN: 0091-6749 |
| ispartof | Journal of allergy and clinical immunology, 2012-12, Vol.130 (6), p.1418-1420.e4 |
| issn | 0091-6749 1097-6825 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Allergens - immunology Allergies Allergy and Immunology Epitope Mapping Epitopes - immunology Female Follow-Up Studies Humans Hypersensitivity - immunology Immunization Immunoglobulin E - blood Immunoglobulin E - immunology Male Microarray Analysis Middle Aged Patients Retrospective Studies Studies |
| title | Analysis of serum IgE reactivity profiles with microarrayed allergens indicates absence of de novo IgE sensitizations in adults |
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