Functional chromatographic technique for natural product isolation

Functional chromatographic technique for natural product isolation

Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional ch...

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Veröffentlicht in:Organic & biomolecular chemistry 2015-02, Vol.13 (8), p.2255-2259
Hauptverfasser: Lau, Eric C, Mason, Damian J, Eichhorst, Nicole, Engelder, Pearce, Mesa, Celestina, Kithsiri Wijeratne, E M, Gunaherath, G M Kamal B, Gunatilaka, A A Leslie, La Clair, James J, Chapman, Eli
Format: Artikel
Sprache:eng
Schlagworte:
Biological Products - chemistry
Biological Products - isolation & purification
Chromatography
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Zusammenfassung:Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation.
ISSN:1477-0520
1477-0539
DOI:10.1039/c4ob02292k