Bridging animal and human models of exercise-induced brain plasticity

Highlights • Physical activity is beneficial for the brain. • Mechanistic pathways have been studied in animals and humans. • Growth factors play an important role in mediating the positive effects of exercise. • Evidence is strong for benefits on the structure and function of the hippocampus. • Phy...

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Veröffentlicht in:	Trends in cognitive sciences 2013-10, Vol.17 (10), p.525-544
Hauptverfasser:	Voss, Michelle W, Vivar, Carmen, Kramer, Arthur F, van Praag, Henriette
Format:	Artikel
Sprache:	eng
Schlagworte:	Anatomical correlates of behavior Animals Behavioral psychophysiology Biological and medical sciences Brain - physiology Brain-Derived Neurotrophic Factor - physiology Cognition - physiology Epigenesis, Genetic - physiology Exercise - physiology Fundamental and applied biological sciences. Psychology Hippocampus - physiology Humans Intercellular Signaling Peptides and Proteins - physiology Neurogenesis - physiology Neurology Neuronal Plasticity - physiology Psychiatry Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology
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Beschreibung
Zusammenfassung:	Highlights • Physical activity is beneficial for the brain. • Mechanistic pathways have been studied in animals and humans. • Growth factors play an important role in mediating the positive effects of exercise. • Evidence is strong for benefits on the structure and function of the hippocampus. • Physical activity benefits all ages and many neurodegenerative diseases.
ISSN:	1364-6613 1879-307X
DOI:	10.1016/j.tics.2013.08.001