Causes and consequences of adult laryngotracheal stenosis

Objectives/Hypothesis Laryngotracheal stenosis (LTS) is largely considered a structural entity, defined on anatomic terms (i.e., percent stenosis, distance from vocal folds, overall length). This has significant implications for identifying at‐risk populations, devising systems‐based preventive stra...

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Veröffentlicht in:The Laryngoscope 2015-05, Vol.125 (5), p.1137-1143
Hauptverfasser: Gelbard, Alexander, Francis, David O., Sandulache, Vlad C., Simmons, John C., Donovan, Donald T., Ongkasuwan, Julina
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Sprache:eng
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Zusammenfassung:Objectives/Hypothesis Laryngotracheal stenosis (LTS) is largely considered a structural entity, defined on anatomic terms (i.e., percent stenosis, distance from vocal folds, overall length). This has significant implications for identifying at‐risk populations, devising systems‐based preventive strategies, and promoting patient‐centered treatment. The present study was undertaken to test the hypothesis that LTS is heterogeneous with regard to etiology, natural history, and clinical outcome. Study Design Retrospective cohort study of consecutive adult tracheal stenosis patients from 1998 to 2013. Methods Subjects diagnosed with laryngotracheal stenosis (ICD‐9: 478.74, 519.19) between January 1, 1998, and January 1, 2013, were identified. Patient characteristics (age, gender, race, follow‐up duration) and comorbidities were extracted. Records were reviewed for etiology of stenosis, treatment approach, and surgical dates. Stenosis morphology was derived from intraoperative measurements. The presence of tracheostomy at last follow‐up was recorded. Results One hundred and fifty patients met inclusion criteria. A total of 54.7% had an iatrogenic etiology, followed by idiopathic (18.5%), autoimmune (18.5%), and traumatic (8%). Tracheostomy dependence differed based on etiology (P 
ISSN:0023-852X
1531-4995
DOI:10.1002/lary.24956