Effect of the 13-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization by Streptococcus pneumoniae—Alaska, 2008-2012

Effect of the 13-Valent Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization by Streptococcus pneumoniae—Alaska, 2008-2012

Background. In 2010, a 13-valent pneumococcal conjugate vaccine (PCV13) replaced a 7-valent vaccine (PCV7) that contained all PCV7 serotypes plus 6 additional serotypes (PCV6+). We conducted annual surveys from 2008 to 2012 to determine the effect of PCV13 on colonization by pneumococcal serotypes....

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Veröffentlicht in:The Journal of infectious diseases 2014-04, Vol.209 (8), p.1251-1258
Hauptverfasser: Gounder, Prabhu P., Bruce, Michael G., Bruden, Dana J. T., Singleton, Rosalyn J., Rudolph, Karen, Hurlburt, Debby A., Hennessy, Thomas W., Wenger, Jay
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adults
Age
Age groups
Alaska - epidemiology
Applied microbiology
BACTERIA
Bacteriology
Biological and medical sciences
Child
Child health services
Child, Preschool
Conjugate vaccines
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Humans
Infectious diseases
Male
Medical sciences
Microbiology
Miscellaneous
Nasopharyngeal Diseases - epidemiology
Nasopharyngeal Diseases - microbiology
Nasopharyngeal Diseases - prevention & control
Nasopharynx - microbiology
Parkinson disease
Pneumococcal Infections - epidemiology
Pneumococcal Infections - microbiology
Pneumococcal Infections - prevention & control
Pneumococcal vaccines
Pneumococcal Vaccines - administration & dosage
Prevalence
Rural Population
Streptococcus
Streptococcus pneumoniae
Streptococcus pneumoniae - isolation & purification
Urban Population
Vaccination
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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Zusammenfassung:Background. In 2010, a 13-valent pneumococcal conjugate vaccine (PCV13) replaced a 7-valent vaccine (PCV7) that contained all PCV7 serotypes plus 6 additional serotypes (PCV6+). We conducted annual surveys from 2008 to 2012 to determine the effect of PCV13 on colonization by pneumococcal serotypes. Methods. We obtained nasopharyngeal swabs for pneumococcal identification and serotyping from residents of all ages at 8 rural villages and children age
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/jit642