Pitfalls in the management of herpes simplex virus encephalitis

We report a case of Herpes Simplex Virus Encephalitis (HSVE) with a fatal outcome of a patient in his 70s presenting to a local teaching hospital with fever and confusion. We highlight pertinent issues regarding diagnosis, investigation and management, and consider ways of improving clinical outcome...

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Veröffentlicht in:	BMJ case reports 2012-10, Vol.2012, p.bcr2012007081
Hauptverfasser:	Ibitoye, Richard Tolulope, Sarkar, Pamela, Rajbhandari, Satyan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Bacterial Agents - therapeutic use Antiviral Agents - therapeutic use Ataxia Blood Glucose - analysis Coma Confusion - etiology Consciousness Cytomegalovirus Delirium Diagnosis, Differential DNA, Viral - cerebrospinal fluid Electroencephalography Encephalitis Encephalitis, Herpes Simplex - diagnosis Encephalitis, Herpes Simplex - drug therapy Family medical history Fatal Outcome Fever Fever - etiology Glucose Glucose - cerebrospinal fluid Herpes viruses Humans Illnesses Learning from Errors Magnetic Resonance Imaging Male Meningitis Mortality NMR Nuclear magnetic resonance Patients Physical Examination Respiratory distress syndrome United Kingdom White
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Zusammenfassung:	We report a case of Herpes Simplex Virus Encephalitis (HSVE) with a fatal outcome of a patient in his 70s presenting to a local teaching hospital with fever and confusion. We highlight pertinent issues regarding diagnosis, investigation and management, and consider ways of improving clinical outcomes. Finally, we discuss the differential diagnoses of acute encephalitis and review the management of HSVE.
ISSN:	1757-790X 1757-790X
DOI:	10.1136/bcr-2012-007081