Correlation between the protein expression of A-kinase anchor protein 95, cyclin D3 and AKT and pathological indicators in lung cancer tissues

The aim of the present study was to investigate the correlation between the protein expression of A-kinase anchor protein 95 (AKAP95), cyclin D3 and AKT with pathological indicators in lung cancer tissues. Immunohistochemistry was used to detect the protein expression levels of the proteins in 51 lu...

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Veröffentlicht in:	Experimental and therapeutic medicine 2015-09, Vol.10 (3), p.1175-1181
Hauptverfasser:	YU, XIUYI, YUAN, YANGYANG, ZHI, XUEHONG, TENG, BOGANG, CHEN, XIAOXUAN, HUANG, QIAN, CHEN, YUEXIN, GUAN, ZHIYU, ZHANG, YONGXING
Format:	Artikel
Sprache:	eng
Schlagworte:	A-kinase anchor protein 95 AKT biomarkers Cell growth cyclin D3 Cyclin-dependent kinases Development and progression diagnosis Kinases Lung cancer Medical diagnosis Pathology Physiological aspects Protein kinases
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Zusammenfassung:	The aim of the present study was to investigate the correlation between the protein expression of A-kinase anchor protein 95 (AKAP95), cyclin D3 and AKT with pathological indicators in lung cancer tissues. Immunohistochemistry was used to detect the protein expression levels of the proteins in 51 lung cancer tissue samples and 15 pericarcinoma tissue samples. The percentage of cyclin D3 positive samples in the lung cancer and pericarcinoma tissues was 68.63 and 28.57%, respectively, and the difference was statistically significant (P
ISSN:	1792-0981 1792-1015
DOI:	10.3892/etm.2015.2637