Fatal Case of Polymicrobial Meningitis Caused by Cryptococcus liquefaciens and Mycobacterium tuberculosis Complex in a Human Immunodeficiency Virus-Infected Patient

Fatal Case of Polymicrobial Meningitis Caused by Cryptococcus liquefaciens and Mycobacterium tuberculosis Complex in a Human Immunodeficiency Virus-Infected Patient

We describe a fatal case of polymicrobial meningitis in a human immunodeficiency virus-infected patient from Guatemala caused by Cryptococcus liquefaciens and Mycobacterium tuberculosis complex. Central nervous system infections caused concurrently by these species are extremely rare. This is also t...

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Veröffentlicht in:Journal of clinical microbiology 2015-08, Vol.53 (8), p.2753-2755
Hauptverfasser: Conde-Pereira, César, Rodas-Rodríguez, Lia, Díaz-Paz, Manuel, Palacios-Rivera, Hilda, Firacative, Carolina, Meyer, Wieland, Alcázar-Castillo, Myriam
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Case Reports
Cluster Analysis
Coinfection - diagnosis
Coinfection - pathology
Cryptococcus
Cryptococcus - isolation & purification
DNA, Fungal - chemistry
DNA, Fungal - genetics
DNA, Ribosomal Spacer - chemistry
DNA, Ribosomal Spacer - genetics
Fatal Outcome
Female
Guatemala
HIV Infections - complications
Humans
Meningitis, Cryptococcal - complications
Meningitis, Cryptococcal - diagnosis
Meningitis, Cryptococcal - pathology
Molecular Sequence Data
Mycobacterium tuberculosis
Mycobacterium tuberculosis - isolation & purification
Phylogeny
Sequence Analysis, DNA
Tuberculosis, Meningeal - complications
Tuberculosis, Meningeal - diagnosis
Tuberculosis, Meningeal - pathology
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Zusammenfassung:We describe a fatal case of polymicrobial meningitis in a human immunodeficiency virus-infected patient from Guatemala caused by Cryptococcus liquefaciens and Mycobacterium tuberculosis complex. Central nervous system infections caused concurrently by these species are extremely rare. This is also the first report of disseminated disease caused by C. liquefaciens.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.00840-15