A cross-sectional study of the prevalence and associations of iron deficiency in a cohort of patients with chronic obstructive pulmonary disease

ObjectivesChronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality. Iron deficiency, with or without anaemia, is associated with other chronic conditions, such as congestive heart failure, where it predicts a worse outcome. However, the prevalence of iron deficiency i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMJ open 2015-07, Vol.5 (7), p.e007911-e007911
Hauptverfasser:	Nickol, Annabel H, Frise, Matthew C, Cheng, Hung-Yuan, McGahey, Anne, McFadyen, Bethan M, Harris-Wright, Tara, Bart, Nicole K, Curtis, M Kate, Khandwala, Shivani, O'Neill, David P, Pollard, Karen A, Hardinge, F Maxine, Rahman, Najib M, Armitage, Andrew E, Dorrington, Keith L, Drakesmith, Hal, Ratcliffe, Peter J, Robbins, Peter A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anemia Biomarkers - metabolism C-Reactive Protein - metabolism Chronic illnesses Chronic obstructive pulmonary disease Cross-Sectional Studies Exercise Exercise Tolerance - physiology Female Ferritins - metabolism Forced Expiratory Volume - physiology Hemoglobin Hemoglobins - metabolism Hepcidins - metabolism Humans Hypoxia Hypoxia - epidemiology Hypoxia - etiology Hypoxia - physiopathology Inflammation Iron Iron Deficiencies Laboratories Male Oxygen therapy Pathophysiology Patients Pneumonia - complications Pneumonia - epidemiology Pneumonia - physiopathology Prevalence Pulmonary Disease, Chronic Obstructive - complications Pulmonary Disease, Chronic Obstructive - epidemiology Pulmonary Disease, Chronic Obstructive - physiopathology Pulmonary hypertension Respiratory Medicine Vital Capacity - physiology White people
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	ObjectivesChronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality. Iron deficiency, with or without anaemia, is associated with other chronic conditions, such as congestive heart failure, where it predicts a worse outcome. However, the prevalence of iron deficiency in COPD is unknown. This observational study aimed to determine the prevalence of iron deficiency in COPD and associations with differences in clinical phenotype.SettingUniversity hospital outpatient clinic.Participants113 adult patients (65% male) with COPD diagnosed according to GOLD criteria (forced expiratory volume in 1 s (FEV1): forced vital capacity (FVC) ratio
ISSN:	2044-6055 2044-6055
DOI:	10.1136/bmjopen-2015-007911