Primaquine dosing errors: the human cost of a pharmaceutical anachronism
Confusion between salt/base forms of primaquine may result in malaria prophylaxis failure. During 1995-2011, there were 14 malaria cases in Israel despite primaquine primary prophylaxis. In 6/14 cases, primaquine was underdosed because of confusion between salt and base forms, including two Plasmodi...
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| Veröffentlicht in: | The American journal of tropical medicine and hygiene 2015-07, Vol.93 (1), p.123-124 |
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| container_title | The American journal of tropical medicine and hygiene |
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| creator | Meltzer, Eyal Morrison, Lindsay Stienlauf, Shmuel Schwartz, Eli |
| description | Confusion between salt/base forms of primaquine may result in malaria prophylaxis failure. During 1995-2011, there were 14 malaria cases in Israel despite primaquine primary prophylaxis. In 6/14 cases, primaquine was underdosed because of confusion between salt and base forms, including two Plasmodium falciparum cases. Primaquine labeling clarification may be lifesaving. |
| doi_str_mv | 10.4269/ajtmh.14-0109 |
| format | Article |
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| ispartof | The American journal of tropical medicine and hygiene, 2015-07, Vol.93 (1), p.123-124 |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Antimalarials - administration & dosage Chemoprevention Cohort Studies Dosage Forms Female Humans Israel Malaria, Falciparum - prevention & control Malaria, Vivax - prevention & control Male Medication Errors Plasmodium falciparum Primaquine - administration & dosage Retrospective Studies Young Adult |
| title | Primaquine dosing errors: the human cost of a pharmaceutical anachronism |
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