The ubiquitous nature of multivesicular release

The ubiquitous nature of multivesicular release

Highlights • Multivesicular release (MVR) enhances the reliability of synaptic transmission throughout the brain. • MVR controls local synaptic integration and network function. • Modulation of MVR on various timescales increases the dynamic range of synapses.

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Bibliographische Detailangaben
Veröffentlicht in:Trends in neurosciences (Regular ed.) 2015-07, Vol.38 (7), p.428-438
Hauptverfasser: Rudolph, Stephanie, Tsai, Ming-Chi, von Gersdorff, Henrique, Wadiche, Jacques I
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Brain
Brain - physiology
Dispersion
Fusion
Humans
Neurology
Neurons
Neurons - cytology
Neurosciences
Neurotransmitter Agents - metabolism
Neurotransmitters
Probability
Synapses - physiology
Synaptic Vesicles - metabolism
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Beschreibung
Zusammenfassung:Highlights • Multivesicular release (MVR) enhances the reliability of synaptic transmission throughout the brain. • MVR controls local synaptic integration and network function. • Modulation of MVR on various timescales increases the dynamic range of synapses.
ISSN:0166-2236
1878-108X
DOI:10.1016/j.tins.2015.05.008