Astrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2

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Veröffentlicht in:Neuroscience 2015-08, Vol.300, p.508-517
Hauptverfasser: Yang, X, Sheng, W, Ridgley, D.M, Haidekker, M.A, Sun, G.Y, Lee, J.C
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container_end_page 517
container_issue
container_start_page 508
container_title Neuroscience
container_volume 300
creator Yang, X
Sheng, W
Ridgley, D.M
Haidekker, M.A
Sun, G.Y
Lee, J.C
description Graphical abstract
doi_str_mv 10.1016/j.neuroscience.2015.05.052
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subjects Amyloid beta-Peptides - metabolism
Amyloid Precursor Protein Secretases - metabolism
astrocytes
Astrocytes - drug effects
Astrocytes - metabolism
Blotting, Western
Cell Line, Tumor
Cell Membrane - drug effects
Cell Membrane - enzymology
Cell Membrane - secretion
Cell Survival
Culture Media, Conditioned
cytokine
Fluorescent Antibody Technique
Group II Phospholipases A2 - antagonists & inhibitors
Group II Phospholipases A2 - metabolism
Humans
membrane fluidity
Membrane Fluidity - drug effects
Membrane Fluidity - physiology
Microscopy, Fluorescence
Neurology
Neurons - drug effects
Neurons - enzymology
Neurons - secretion
Peptide Fragments - metabolism
sAPPα
SH-SY5Y
sPLA2-IIA
title Astrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2
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