Astrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2

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Veröffentlicht in:	Neuroscience 2015-08, Vol.300, p.508-517
Hauptverfasser:	Yang, X, Sheng, W, Ridgley, D.M, Haidekker, M.A, Sun, G.Y, Lee, J.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid beta-Peptides - metabolism Amyloid Precursor Protein Secretases - metabolism astrocytes Astrocytes - drug effects Astrocytes - metabolism Blotting, Western Cell Line, Tumor Cell Membrane - drug effects Cell Membrane - enzymology Cell Membrane - secretion Cell Survival Culture Media, Conditioned cytokine Fluorescent Antibody Technique Group II Phospholipases A2 - antagonists & inhibitors Group II Phospholipases A2 - metabolism Humans membrane fluidity Membrane Fluidity - drug effects Membrane Fluidity - physiology Microscopy, Fluorescence Neurology Neurons - drug effects Neurons - enzymology Neurons - secretion Peptide Fragments - metabolism sAPPα SH-SY5Y sPLA2-IIA
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