Detection and Phenotyping of Circulating Tumor Cells in High-Risk Localized Prostate Cancer
Micro-Abstract Circulating tumor cells (CTCs) have established prognostic value in the setting of metastatic castration-resistant prostate cancer. However, their utility in the setting of localized prostate cancer is largely unknown. In the current study, a novel method was used to quantify and char...
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| Veröffentlicht in: | Clinical genitourinary cancer 2015-04, Vol.13 (2), p.130-136 |
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| container_title | Clinical genitourinary cancer |
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| creator | Pal, Sumanta K He, Miaoling Wilson, Timothy Liu, Xueli Zhang, Keqiang Carmichael, Courtney Torres, Alejandra Hernandez, Sonya Lau, Clayton Agarwal, Neeraj Kawachi, Mark Yen, Yun Jones, Jeremy O |
| description | Micro-Abstract Circulating tumor cells (CTCs) have established prognostic value in the setting of metastatic castration-resistant prostate cancer. However, their utility in the setting of localized prostate cancer is largely unknown. In the current study, a novel method was used to quantify and characterize CTCs in patients with high-risk localized prostate cancer (HRLPC). |
| doi_str_mv | 10.1016/j.clgc.2014.08.014 |
| format | Article |
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However, their utility in the setting of localized prostate cancer is largely unknown. In the current study, a novel method was used to quantify and characterize CTCs in patients with high-risk localized prostate cancer (HRLPC).</description><identifier>ISSN: 1558-7673</identifier><identifier>EISSN: 1938-0682</identifier><identifier>DOI: 10.1016/j.clgc.2014.08.014</identifier><identifier>PMID: 25450039</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>AC133 Antigen ; Aged ; Antigens, CD - metabolism ; Biomarkers, Tumor - metabolism ; Cadherins - metabolism ; CD133 ; Cell Count ; Cell Separation - methods ; CellSearch ; EMT ; Epithelial-Mesenchymal Transition ; Feasibility Studies ; Fragment ; Glycoproteins - metabolism ; Hematology, Oncology and Palliative Medicine ; Humans ; Male ; Middle Aged ; Neoplastic Cells, Circulating - metabolism ; Neoplastic Cells, Circulating - pathology ; Peptides - metabolism ; Phenotype ; Prognosis ; Prospective Studies ; Prostatic Neoplasms - blood ; Prostatic Neoplasms - pathology ; Stem cell ; Urology</subject><ispartof>Clinical genitourinary cancer, 2015-04, Vol.13 (2), p.130-136</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><rights>2014 Published by Elsevier Inc. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c646t-5eb06bd7a43b184f39fb6497a735be2910d7b2e6fb123bec44f872064c4609d93</citedby><cites>FETCH-LOGICAL-c646t-5eb06bd7a43b184f39fb6497a735be2910d7b2e6fb123bec44f872064c4609d93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25450039$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pal, Sumanta K</creatorcontrib><creatorcontrib>He, Miaoling</creatorcontrib><creatorcontrib>Wilson, Timothy</creatorcontrib><creatorcontrib>Liu, Xueli</creatorcontrib><creatorcontrib>Zhang, Keqiang</creatorcontrib><creatorcontrib>Carmichael, Courtney</creatorcontrib><creatorcontrib>Torres, Alejandra</creatorcontrib><creatorcontrib>Hernandez, Sonya</creatorcontrib><creatorcontrib>Lau, Clayton</creatorcontrib><creatorcontrib>Agarwal, Neeraj</creatorcontrib><creatorcontrib>Kawachi, Mark</creatorcontrib><creatorcontrib>Yen, Yun</creatorcontrib><creatorcontrib>Jones, Jeremy O</creatorcontrib><title>Detection and Phenotyping of Circulating Tumor Cells in High-Risk Localized Prostate Cancer</title><title>Clinical genitourinary cancer</title><addtitle>Clin Genitourin Cancer</addtitle><description>Micro-Abstract Circulating tumor cells (CTCs) have established prognostic value in the setting of metastatic castration-resistant prostate cancer. 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In the current study, a novel method was used to quantify and characterize CTCs in patients with high-risk localized prostate cancer (HRLPC).</description><subject>AC133 Antigen</subject><subject>Aged</subject><subject>Antigens, CD - metabolism</subject><subject>Biomarkers, Tumor - metabolism</subject><subject>Cadherins - metabolism</subject><subject>CD133</subject><subject>Cell Count</subject><subject>Cell Separation - methods</subject><subject>CellSearch</subject><subject>EMT</subject><subject>Epithelial-Mesenchymal Transition</subject><subject>Feasibility Studies</subject><subject>Fragment</subject><subject>Glycoproteins - metabolism</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplastic Cells, Circulating - metabolism</subject><subject>Neoplastic Cells, Circulating - pathology</subject><subject>Peptides - metabolism</subject><subject>Phenotype</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Prostatic Neoplasms - blood</subject><subject>Prostatic Neoplasms - pathology</subject><subject>Stem cell</subject><subject>Urology</subject><issn>1558-7673</issn><issn>1938-0682</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kk9v1DAQxSMEoqXwBTigHLkkjP_ETiRUCYVCK60EgnLiYDnOZNfbrL3YSaXtp8fRlqpw4DS2_N6zZ37OstcESgJEvNuWZlybkgLhJdRlKk-yU9KwugBR06dpXVV1IYVkJ9mLGLcAvCISnmcntOIVAGtOs58fcUIzWe9y7fr86wadnw5769a5H_LWBjOPelq21_POh7zFcYy5dfmlXW-Kbzbe5Ctv9GjvMLmDj5OeMG-1MxheZs8GPUZ8dV_Psh-fLq7by2L15fNV-2FVGMHFVFTYgeh6qTnrSM0H1gyd4I3UklUd0oZALzuKYugIZR0azodaUhDccAFN37Cz7PyYu5-7HfYG3RT0qPbB7nQ4KK-t-vvE2Y1a-1vFuWyoYCng7X1A8L9mjJPa2WhSp9qhn6MiQnAKnMoqSelRalKvMeDwcA0BtVBRW7VQUQsVBbVKJZnePH7gg-UPhiR4fxRgGtOtxaCisZhm2NuQ6Kje2__nn_9jN6N1NmG5wQPGrZ-DSwAUUZEqUN-Xf7F8C8IBKMiG_QZGc7Pa</recordid><startdate>20150401</startdate><enddate>20150401</enddate><creator>Pal, Sumanta K</creator><creator>He, Miaoling</creator><creator>Wilson, Timothy</creator><creator>Liu, Xueli</creator><creator>Zhang, Keqiang</creator><creator>Carmichael, Courtney</creator><creator>Torres, Alejandra</creator><creator>Hernandez, Sonya</creator><creator>Lau, Clayton</creator><creator>Agarwal, Neeraj</creator><creator>Kawachi, Mark</creator><creator>Yen, Yun</creator><creator>Jones, Jeremy O</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150401</creationdate><title>Detection and Phenotyping of Circulating Tumor Cells in High-Risk Localized Prostate Cancer</title><author>Pal, Sumanta K ; He, Miaoling ; Wilson, Timothy ; Liu, Xueli ; Zhang, Keqiang ; Carmichael, Courtney ; Torres, Alejandra ; Hernandez, Sonya ; Lau, Clayton ; Agarwal, Neeraj ; Kawachi, Mark ; Yen, Yun ; Jones, Jeremy O</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c646t-5eb06bd7a43b184f39fb6497a735be2910d7b2e6fb123bec44f872064c4609d93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>AC133 Antigen</topic><topic>Aged</topic><topic>Antigens, CD - metabolism</topic><topic>Biomarkers, Tumor - metabolism</topic><topic>Cadherins - metabolism</topic><topic>CD133</topic><topic>Cell Count</topic><topic>Cell Separation - methods</topic><topic>CellSearch</topic><topic>EMT</topic><topic>Epithelial-Mesenchymal Transition</topic><topic>Feasibility Studies</topic><topic>Fragment</topic><topic>Glycoproteins - metabolism</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplastic Cells, Circulating - metabolism</topic><topic>Neoplastic Cells, Circulating - pathology</topic><topic>Peptides - metabolism</topic><topic>Phenotype</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Prostatic Neoplasms - blood</topic><topic>Prostatic Neoplasms - pathology</topic><topic>Stem cell</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pal, Sumanta K</creatorcontrib><creatorcontrib>He, Miaoling</creatorcontrib><creatorcontrib>Wilson, Timothy</creatorcontrib><creatorcontrib>Liu, Xueli</creatorcontrib><creatorcontrib>Zhang, Keqiang</creatorcontrib><creatorcontrib>Carmichael, Courtney</creatorcontrib><creatorcontrib>Torres, Alejandra</creatorcontrib><creatorcontrib>Hernandez, Sonya</creatorcontrib><creatorcontrib>Lau, Clayton</creatorcontrib><creatorcontrib>Agarwal, Neeraj</creatorcontrib><creatorcontrib>Kawachi, Mark</creatorcontrib><creatorcontrib>Yen, Yun</creatorcontrib><creatorcontrib>Jones, Jeremy O</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Clinical genitourinary cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pal, Sumanta K</au><au>He, Miaoling</au><au>Wilson, Timothy</au><au>Liu, Xueli</au><au>Zhang, Keqiang</au><au>Carmichael, Courtney</au><au>Torres, Alejandra</au><au>Hernandez, Sonya</au><au>Lau, Clayton</au><au>Agarwal, Neeraj</au><au>Kawachi, Mark</au><au>Yen, Yun</au><au>Jones, Jeremy O</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection and Phenotyping of Circulating Tumor Cells in High-Risk Localized Prostate Cancer</atitle><jtitle>Clinical genitourinary cancer</jtitle><addtitle>Clin Genitourin Cancer</addtitle><date>2015-04-01</date><risdate>2015</risdate><volume>13</volume><issue>2</issue><spage>130</spage><epage>136</epage><pages>130-136</pages><issn>1558-7673</issn><eissn>1938-0682</eissn><abstract>Micro-Abstract Circulating tumor cells (CTCs) have established prognostic value in the setting of metastatic castration-resistant prostate cancer. 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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | AC133 Antigen Aged Antigens, CD - metabolism Biomarkers, Tumor - metabolism Cadherins - metabolism CD133 Cell Count Cell Separation - methods CellSearch EMT Epithelial-Mesenchymal Transition Feasibility Studies Fragment Glycoproteins - metabolism Hematology, Oncology and Palliative Medicine Humans Male Middle Aged Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology Peptides - metabolism Phenotype Prognosis Prospective Studies Prostatic Neoplasms - blood Prostatic Neoplasms - pathology Stem cell Urology |
| title | Detection and Phenotyping of Circulating Tumor Cells in High-Risk Localized Prostate Cancer |
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