Detection and Phenotyping of Circulating Tumor Cells in High-Risk Localized Prostate Cancer

Micro-Abstract Circulating tumor cells (CTCs) have established prognostic value in the setting of metastatic castration-resistant prostate cancer. However, their utility in the setting of localized prostate cancer is largely unknown. In the current study, a novel method was used to quantify and char...

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Veröffentlicht in:	Clinical genitourinary cancer 2015-04, Vol.13 (2), p.130-136
Hauptverfasser:	Pal, Sumanta K, He, Miaoling, Wilson, Timothy, Liu, Xueli, Zhang, Keqiang, Carmichael, Courtney, Torres, Alejandra, Hernandez, Sonya, Lau, Clayton, Agarwal, Neeraj, Kawachi, Mark, Yen, Yun, Jones, Jeremy O
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Aged Antigens, CD - metabolism Biomarkers, Tumor - metabolism Cadherins - metabolism CD133 Cell Count Cell Separation - methods CellSearch EMT Epithelial-Mesenchymal Transition Feasibility Studies Fragment Glycoproteins - metabolism Hematology, Oncology and Palliative Medicine Humans Male Middle Aged Neoplastic Cells, Circulating - metabolism Neoplastic Cells, Circulating - pathology Peptides - metabolism Phenotype Prognosis Prospective Studies Prostatic Neoplasms - blood Prostatic Neoplasms - pathology Stem cell Urology
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Zusammenfassung:	Micro-Abstract Circulating tumor cells (CTCs) have established prognostic value in the setting of metastatic castration-resistant prostate cancer. However, their utility in the setting of localized prostate cancer is largely unknown. In the current study, a novel method was used to quantify and characterize CTCs in patients with high-risk localized prostate cancer (HRLPC).
ISSN:	1558-7673 1938-0682
DOI:	10.1016/j.clgc.2014.08.014