Metal rich particulate matter impairs acetylcholine-mediated vasorelaxation of microvessels in mice

Exposure to PM2.5 (particulate matter

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Bibliographische Detailangaben
Veröffentlicht in:	Particle and fibre toxicology 2015-06, Vol.12 (1), p.14, Article 14
Hauptverfasser:	Cuevas, Azita K, Niu, Jingping, Zhong, Mianhua, Liberda, Eric N, Ghio, Andrew, Qu, Qingshan, Chen, Lung Chi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Acetylcholine - pharmacology Air pollution Animals Arsenic Arsenic - chemistry Arsenic - toxicity Biomarkers - blood Blood vessels Bronchoalveolar Lavage Fluid - chemistry Bronchoalveolar Lavage Fluid - cytology Copper - chemistry Copper - toxicity Cytokines - blood Dilatation Dose-Response Relationship, Drug Endothelium Endothelium, Vascular - drug effects Endothelium, Vascular - physiopathology Environmental aspects Gene expression Health aspects Inflammation Male Mice, Inbred Strains Microvessels - drug effects Microvessels - physiopathology Nickel - analysis Nickel - chemistry Nickel - toxicity Oxidases Particle Size Particulate Matter - analysis Particulate Matter - chemistry Particulate Matter - toxicity Phenylephrine Respiratory Aspiration - chemically induced Respiratory Aspiration - immunology Respiratory Aspiration - physiopathology Selenium Selenium - chemistry Selenium - toxicity Sodium nitroferricyanide Vascular endothelial growth factor Vasodilation - drug effects
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Beschreibung
Zusammenfassung:	Exposure to PM2.5 (particulate matter
ISSN:	1743-8977 1743-8977
DOI:	10.1186/s12989-014-0077-x