The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy

A new efficient type of gadolinium-based theranostic agent (AGuIX®) has recently been developed for MRI-guided radiotherapy (RT). These new particles consist of a polysiloxane network surrounded by a number of gadolinium chelates, usually 10. Owing to their small size (

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Veröffentlicht in:	British journal of radiology 2014-09, Vol.87 (1041), p.20140134
Hauptverfasser:	Sancey, L, Lux, F, Kotb, S, Roux, S, Dufort, S, Bianchi, A, Crémillieux, Y, Fries, P, Coll, J-L, Rodriguez-Lafrasse, C, Janier, M, Dutreix, M, Barberi-Heyob, M, Boschetti, F, Denat, F, Louis, C, Porcel, E, Lacombe, S, Le Duc, G, Deutsch, E, Perfettini, J-L, Detappe, A, Verry, C, Berbeco, R, Butterworth, K T, McMahon, S J, Prise, K M, Perriat, P, Tillement, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer Contrast Media Gadolinium Humans Life Sciences Magnetic Resonance Imaging Mice Models, Theoretical Nanoparticles Neoplasms - drug therapy Neoplasms - radiotherapy Radiation-Sensitizing Agents - chemistry Radiotherapy and Oncology Review Siloxanes
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Beschreibung
Zusammenfassung:	A new efficient type of gadolinium-based theranostic agent (AGuIX®) has recently been developed for MRI-guided radiotherapy (RT). These new particles consist of a polysiloxane network surrounded by a number of gadolinium chelates, usually 10. Owing to their small size (
ISSN:	0007-1285 1748-880X
DOI:	10.1259/bjr.20140134