Low 25-hydroxyvitamin D concentrations predict incident depression in well-functioning older adults: the health, aging, and body composition study

Cross-sectional studies suggest that low 25-hydroxyvitamin D (25[OH]D) may be a risk factor for depression; however, there are few prospective studies. We examined the association between 25(OH)D and depressive symptoms in community-dwelling persons aged 70-79 years in the Health, Aging, and Body Co...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2015-06, Vol.70 (6), p.757-763
Hauptverfasser:	Williams, Julie A, Sink, Kaycee M, Tooze, Janet A, Atkinson, Hal H, Cauley, Jane A, Yaffe, Kristine, Tylavsky, Frances A, Rubin, Susan M, Simonsick, Eleanor M, Kritchevsky, Stephen B, Houston, Denise K
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Antidepressive Agents - therapeutic use Black or African American Black People Depression - blood Depression - drug therapy Depression - epidemiology Epidemiology Female Follow-Up Studies Geriatric psychology Geriatrics Humans Incidence Male Mental depression Older people Pennsylvania - epidemiology Proportional Hazards Models Prospective Studies Risk factors Tennessee - epidemiology Vitamin D Vitamin D - analogs & derivatives Vitamin D - blood White People
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Zusammenfassung:	Cross-sectional studies suggest that low 25-hydroxyvitamin D (25[OH]D) may be a risk factor for depression; however, there are few prospective studies. We examined the association between 25(OH)D and depressive symptoms in community-dwelling persons aged 70-79 years in the Health, Aging, and Body Composition (Health ABC) Study (n = 2598). Depressive symptoms were assessed using the Center for Epidemiologic Studies-Depression Scale (CES-D) at baseline and 2-, 3- and 4-year follow-up. Serum 25(OH)D was measured at 1-year follow-up and categorized as
ISSN:	1079-5006 1758-535X 1758-535X
DOI:	10.1093/gerona/glu184