Advanced cancer as a risk for major depressive episodes

Objective Major depression adversely affects health communication, quality of life, and survival in patients with advanced cancer. Prior research provides limited insight into how patients with advanced cancer differ from the general population in risk for developing a major depressive episode (MDE)...

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Veröffentlicht in:	Psycho-oncology (Chichester, England) England), 2015-09, Vol.24 (9), p.1080-1087
Hauptverfasser:	Meyer, Fremonta, Fletcher, Kalen, Prigerson, Holly G., Braun, Ilana M., Maciejewski, Paul K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Psychological Adult Aged Cancer Case-Control Studies Comparative analysis depression Depressive Disorder, Major - epidemiology epidemiology etiology Female Health Surveys Humans Male Mental depression Middle Aged Neoplasms - pathology Neoplasms - psychology oncology Prospective Studies Quality of life Recurrence Risk assessment Risk Factors Severity of Illness Index United States - epidemiology
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Zusammenfassung:	Objective Major depression adversely affects health communication, quality of life, and survival in patients with advanced cancer. Prior research provides limited insight into how patients with advanced cancer differ from the general population in risk for developing a major depressive episode (MDE). This study aims to determine whether advanced cancer poses distinct risks for initial and recurrent MDEs. Methods Advanced cancer patients (N = 628) from Coping with Cancer were compared with propensity‐weighted general population controls (N = 9282) from the National Comorbidity Survey Replication. Results Patients with advanced cancer were more likely than comparisons to have an initial MDE [OR = 27.3, 95% CI = (14.8–50.4); p
ISSN:	1057-9249 1099-1611
DOI:	10.1002/pon.3722