Cortical activation and inter-hemispheric sensorimotor coherence in individuals with arm dystonia due to childhood stroke

Highlights • In individuals with dystonia after childhood stroke, functionally relevant EEG abnormalities can be identified. • Ipsilesional sensorimotor cortical activation in the 8–12 Hz range is abnormally reduced in patients and correlates with weakness of the more affected wrist. • Resting inter...

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Veröffentlicht in:Clinical neurophysiology 2015-08, Vol.126 (8), p.1589-1598
Hauptverfasser: Kukke, Sahana N, de Campos, Ana Carolina, Damiano, Diane, Alter, Katharine E, Patronas, Nicholas, Hallett, Mark
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Sprache:eng
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Zusammenfassung:Highlights • In individuals with dystonia after childhood stroke, functionally relevant EEG abnormalities can be identified. • Ipsilesional sensorimotor cortical activation in the 8–12 Hz range is abnormally reduced in patients and correlates with weakness of the more affected wrist. • Resting inter-hemispheric sensorimotor connectivity in patients is abnormally reduced and correlates with increased dystonia severity and reduced hand function.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2014.11.002