Evaluation of the Qiagen artus C. difficile QS-RGQ Kit for Detection of Clostridium difficile Toxins A and B in Clinical Stool Specimens

We compared the Qiagen artus C. difficile QS-RGQ kit, a new nucleic acid amplification test for the detection of Clostridium difficile toxins in stool specimens, with the Cepheid Xpert C. difficile test. The sensitivity, specificity, positive predictive value, and negative predictive value for the Q...

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Veröffentlicht in:	Journal of clinical microbiology 2015-06, Vol.53 (6), p.1942-1944
Hauptverfasser:	Jazmati, Nathalie, Wiegel, Pia, Ličanin, Božica, Plum, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - genetics Bacterial Toxins - genetics Bacteriology Clostridium difficile Clostridium difficile - genetics Clostridium Infections - diagnosis Enterotoxins - genetics Feces - microbiology Humans Molecular Typing - methods Reproducibility of Results Sensitivity and Specificity
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Zusammenfassung:	We compared the Qiagen artus C. difficile QS-RGQ kit, a new nucleic acid amplification test for the detection of Clostridium difficile toxins in stool specimens, with the Cepheid Xpert C. difficile test. The sensitivity, specificity, positive predictive value, and negative predictive value for the Qiagen artus C. difficile QS-RGQ test were 100%, 89.5%, 60.9%, and 100%, and those for the Cepheid Xpert C. difficile test were 100%, 90%, 62.2%, and 100%, respectively.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.00613-15