The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses

The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses

Highlight ► The inflammasome is a broad range sensor of danger signals and mediator of psychological and physical stressors that can lead to depression and comorbid illnesses.

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Bibliographische Detailangaben
Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2013-07, Vol.31, p.105-114
Hauptverfasser: Iwata, Masaaki, Ota, Kristie T, Duman, Ronald S
Format: Artikel
Sprache:eng
Schlagworte:
Allergy and Immunology
Antidepressant
Depressive Disorder - complications
Humans
Inflammation - complications
Inflammatory cytokine
Interleukin-1
Models, Theoretical
NLRP3 inflammasome
Psychiatry
Stress, Psychological - complications
Toll like receptor
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Beschreibung
Zusammenfassung:Highlight ► The inflammasome is a broad range sensor of danger signals and mediator of psychological and physical stressors that can lead to depression and comorbid illnesses.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2012.12.008