Evaluation of Oxidative Stress and hsCRP in Polycystic Ovarian Syndrome in a Tertiary Care Hospital

Evaluation of Oxidative Stress and hsCRP in Polycystic Ovarian Syndrome in a Tertiary Care Hospital

PCOS is a heterogeneous endocrine disorder with diverse clinical presentation. Oxidative stress plays a key role in the pathophysiology of this disease. Serumhigh sensitive C-reactive protein (hsCRP), a marker of chronic low grade inflammation, is indicative of future development of cardiovascular d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Indian journal of clinical biochemistry 2015-04, Vol.30 (2), p.161-166
Hauptverfasser: Sumithra, N. Unni C., Lakshmi, R. Lakshman, Leela Menon, N., Subhakumari, K. N., Sheejamol, V. S.
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Biochemistry
Biomedical and Life Sciences
C-reactive protein
Cardiovascular diseases
Chemistry/Food Science
Development and progression
Ethylenediaminetetraacetic acid
Health aspects
Hospitals
Life Sciences
Microbiology
Original
Original Article
Oxidative stress
Pathology
Polycystic ovary syndrome
Prolactin
Stein-Leventhal syndrome
Superoxide
Type 2 diabetes
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:PCOS is a heterogeneous endocrine disorder with diverse clinical presentation. Oxidative stress plays a key role in the pathophysiology of this disease. Serumhigh sensitive C-reactive protein (hsCRP), a marker of chronic low grade inflammation, is indicative of future development of cardiovascular disease. Our aim is to evaluate the oxidant status and hsCRP levels in PCOS. The study involved 61 cases and 61 controls in the age group of 18–40 years diagnosed with PCOS. Erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD), serum hsCRP, gonadotrophins, thyroid stimulating hormone, prolactin, glycemic status and lipid profile were estimated. Erythrocyte MDA ( p  
ISSN:0970-1915
0974-0422
DOI:10.1007/s12291-014-0427-3