Balancing the innate immune system in tumor development

Balancing the innate immune system in tumor development

Highlights • The outcome of the innate immune system is determined by the tumor context. • The balance of innate immune cells dictates the fate of cancer development. • Innate lymphoid cells are important in regulating tumorigenesis. • There is an emerging role for neutrophil subsets in tumor progre...

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Veröffentlicht in:Trends in cell biology 2015-04, Vol.25 (4), p.214-220
Hauptverfasser: Hagerling, Catharina, Casbon, Amy-Jo, Werb, Zena
Format: Artikel
Sprache:eng
Schlagworte:
cancer development
Cell Transformation, Neoplastic - immunology
Disease Progression
Humans
Immunity, Innate
inflammation
Inflammation - immunology
innate immune cells
Neoplasms - immunology
Pathology
Tumor Microenvironment - immunology
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Zusammenfassung:Highlights • The outcome of the innate immune system is determined by the tumor context. • The balance of innate immune cells dictates the fate of cancer development. • Innate lymphoid cells are important in regulating tumorigenesis. • There is an emerging role for neutrophil subsets in tumor progression.
ISSN:0962-8924
1879-3088
DOI:10.1016/j.tcb.2014.11.001