Histones: At the Crossroads of Peptide and Protein Chemistry

Histones: At the Crossroads of Peptide and Protein Chemistry

Issues surrounding the synthesis of modified histone peptides are examined. Topics discussed include histone phosphorylation, lysine methylation and arginine methylation.

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Veröffentlicht in:Chemical reviews 2015-03, Vol.115 (6), p.2296-2349
Hauptverfasser: Müller, Manuel M, Muir, Tom W
Format: Artikel
Sprache:eng
Schlagworte:
Histones - chemistry
Histones - metabolism
Humans
Models, Molecular
Molecular biology
Molecular Structure
Peptides
Peptides - chemistry
Peptides - metabolism
Proteins
Proteins - chemistry
Proteins - metabolism
Review
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Beschreibung
Zusammenfassung:Issues surrounding the synthesis of modified histone peptides are examined. Topics discussed include histone phosphorylation, lysine methylation and arginine methylation.
ISSN:0009-2665
1520-6890
1520-6890
DOI:10.1021/cr5003529