Tetracarpidium conophorum (Mull.Arg) Hutch & Dalziel inhibits FeSO4-induced lipid peroxidation in rat's genitals

To search for new sources of safe and inexpensive antioxidant agents which can be used to treat various oxidative stress-related diseases, the phenolic contents of leaf of Tetracarpidium conophorum were characterized and its effect on pro-oxidant induced oxidative stress in rat's genitals for t...

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Veröffentlicht in:	BMC complementary and alternative medicine 2015-03, Vol.15 (1), p.57-57, Article 57
Hauptverfasser:	Akomolafe, Seun F, Oboh, Ganiyu, Akindahunsi, Afolabi A, Afolayan, Anthony J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antioxidants Antioxidants - analysis Antioxidants - pharmacology Antioxidants - therapeutic use ascorbic acid Ascorbic Acid - analysis Ascorbic Acid - pharmacology Ascorbic Acid - therapeutic use caffeic acid catechin chlorogenic acid complement coumarin dose response Euphorbiaceae - chemistry Flavonoids - analysis Flavonoids - pharmacology Flavonoids - therapeutic use gallic acid genitalia Genitalia, Male - metabolism Health aspects High performance liquid chromatography Infertility, Male - drug therapy Infertility, Male - metabolism Iron Compounds - metabolism kaempferol leaves Lipid peroxidation Lipid Peroxidation - drug effects luteolin Male Oxidation-Reduction oxidative stress Oxidative Stress - drug effects penis Phenols - analysis Phenols - pharmacology Phenols - therapeutic use Phytotherapy Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use Plant Leaves - chemistry quercetin quercitrin rats Rats, Wistar Reactive Oxygen Species - metabolism rutin spectrophotometers Vitamins - analysis Vitamins - pharmacology Vitamins - therapeutic use
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Zusammenfassung:	To search for new sources of safe and inexpensive antioxidant agents which can be used to treat various oxidative stress-related diseases, the phenolic contents of leaf of Tetracarpidium conophorum were characterized and its effect on pro-oxidant induced oxidative stress in rat's genitals for the first time was investigated. The aqueous extract of the plant was prepared, the antioxidant activities of the extract were then evaluated using spectrophotometric method. The result revealed that the introduction of aqueous extract of the plant caused significant concentration-dependent decrease (P
ISSN:	1472-6882 1472-6882
DOI:	10.1186/s12906-015-0547-1