Upper extremity acute compartment syndrome during tissue plasminogen activator therapy for pulmonary embolism in a morbidly obese patient

Highlights • Deep vein thrombosis (DVT) and pulmonary embolism (PE) are more frequently observed morbidly obese patients. • As the use of thrombolytic therapy has become more common in the treatment of myocardial infarction (MI) and PE, acute compartment syndrome (ACS) has been reported as a rare complication of thrombolytic therapy. • As soon as the diagnosis of compartment syndrome is made, an emergency fasciotomy should be performed. • Close follow-up is required to avoid wound healing problems after the fasciotomy.