The oral microbiome and the immunobiology of periodontal disease and caries

Highlights • The core oral microbiome and in various ecological niches. • Microbial ecology of the tooth crown and the gingival sulcus. • Sustained high microbial diversity in periodontal disease status. • Microbial diversity: high in caries initiation and low in established caries. • Immunity of ca...

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Veröffentlicht in:	Immunology letters 2014-12, Vol.162 (2), p.22-38
Hauptverfasser:	Costalonga, Massimo, Herzberg, Mark C
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Caries Dental Caries - immunology Dental Caries - microbiology Dysbiosis - immunology Dysbiosis - microbiology Gingiva - immunology Humans Immunity, Mucosal Immunoglobulin A, Secretory - immunology Microbiome Microbiota - immunology Mouth - immunology Mouth - microbiology Pathogenesis Periodontal Diseases - immunology Periodontal Diseases - microbiology Periodontitis Porphyromonas gingivalis Porphyromonas gingivalis - immunology Streptococcus mutans Streptococcus mutans - immunology
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Beschreibung
Zusammenfassung:	Highlights • The core oral microbiome and in various ecological niches. • Microbial ecology of the tooth crown and the gingival sulcus. • Sustained high microbial diversity in periodontal disease status. • Microbial diversity: high in caries initiation and low in established caries. • Immunity of caries and caries vaccines.
ISSN:	0165-2478 1879-0542
DOI:	10.1016/j.imlet.2014.08.017