Axon guidance and injury — lessons from Wnts and Wnt signaling

Highlights • Wnts are conserved axon guidance molecules for many axons. • Conserved cell polarity signaling components mediate Wnt functions in steering. • Wnts are reinduced in spinal cord injury and regulate axon regeneration.

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Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in neurobiology 2014-08, Vol.27, p.232-240
Hauptverfasser:	Onishi, Keisuke, Hollis, Edmund, Zou, Yimin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axons - physiology Cell Polarity - physiology Neurology Psychiatry Signal Transduction - physiology Spinal Cord Injuries - metabolism Spinal Cord Injuries - pathology Spinal Cord Injuries - physiopathology Wnt Proteins - metabolism
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Beschreibung
Zusammenfassung:	Highlights • Wnts are conserved axon guidance molecules for many axons. • Conserved cell polarity signaling components mediate Wnt functions in steering. • Wnts are reinduced in spinal cord injury and regulate axon regeneration.
ISSN:	0959-4388 1873-6882
DOI:	10.1016/j.conb.2014.05.005