Design and Synthesis of Novel Isoxazole Tethered Quinone-Amino Acid Hybrids
A new series of isoxazole tethered quinone-amino acid hybrids has been designed and synthesized involving 1,3-dipolar cycloaddition reaction followed by an oxidation reaction using cerium ammonium nitrate (CAN). Using this method, for the first time various isoxazole tethered quinone-phenyl alanine...
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| Veröffentlicht in: | Journal of Amino Acids 2014-01, Vol.2014 (2014), p.i1-14 |
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| container_issue | 2014 |
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| container_title | Journal of Amino Acids |
| container_volume | 2014 |
| creator | Ravi Kumar, P. Behera, Manoranjan Sambaiah, M. Kandula, Venu Payili, Nagaraju Jaya Shree, A. Yennam, Satyanarayana |
| description | A new series of isoxazole tethered quinone-amino acid hybrids has been designed and synthesized involving 1,3-dipolar cycloaddition reaction followed by an oxidation reaction using cerium ammonium nitrate (CAN). Using this method, for the first time various isoxazole tethered quinone-phenyl alanine and quinone-alanine hybrids were synthesized from simple commercially available 4-bromobenzyl bromide, propargyl bromide, and 2,5-dimethoxybenzaldehyde in good yield. |
| doi_str_mv | 10.1155/2014/721291 |
| format | Article |
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Using this method, for the first time various isoxazole tethered quinone-phenyl alanine and quinone-alanine hybrids were synthesized from simple commercially available 4-bromobenzyl bromide, propargyl bromide, and 2,5-dimethoxybenzaldehyde in good yield.</description><identifier>ISSN: 2090-0112</identifier><identifier>ISSN: 2090-0104</identifier><identifier>EISSN: 2090-0112</identifier><identifier>DOI: 10.1155/2014/721291</identifier><identifier>PMID: 25709839</identifier><language>eng</language><publisher>Egypt: Hindawi Limiteds</publisher><subject>Amino acids ; Ammonium nitrate ; Antibiotics ; Chromatography ; Natural products ; Quinone ; Synthesis</subject><ispartof>Journal of Amino Acids, 2014-01, Vol.2014 (2014), p.i1-14</ispartof><rights>Copyright © 2014 P. Ravi Kumar et al.</rights><rights>COPYRIGHT 2014 John Wiley & Sons, Inc.</rights><rights>Copyright © 2014 P. Ravi Kumar et al. P. Ravi Kumar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2014 P. Ravi Kumar et al. 2014</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a4231-e081132a414984e5ac1f620791488a6dd868056b6bc80a3310de21b0be7604973</citedby><cites>FETCH-LOGICAL-a4231-e081132a414984e5ac1f620791488a6dd868056b6bc80a3310de21b0be7604973</cites><orcidid>0000-0002-4987-0942</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331483/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331483/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25709839$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kotha, Sambasivarao</contributor><creatorcontrib>Ravi Kumar, P.</creatorcontrib><creatorcontrib>Behera, Manoranjan</creatorcontrib><creatorcontrib>Sambaiah, M.</creatorcontrib><creatorcontrib>Kandula, Venu</creatorcontrib><creatorcontrib>Payili, Nagaraju</creatorcontrib><creatorcontrib>Jaya Shree, A.</creatorcontrib><creatorcontrib>Yennam, Satyanarayana</creatorcontrib><title>Design and Synthesis of Novel Isoxazole Tethered Quinone-Amino Acid Hybrids</title><title>Journal of Amino Acids</title><addtitle>J Amino Acids</addtitle><description>A new series of isoxazole tethered quinone-amino acid hybrids has been designed and synthesized involving 1,3-dipolar cycloaddition reaction followed by an oxidation reaction using cerium ammonium nitrate (CAN). Using this method, for the first time various isoxazole tethered quinone-phenyl alanine and quinone-alanine hybrids were synthesized from simple commercially available 4-bromobenzyl bromide, propargyl bromide, and 2,5-dimethoxybenzaldehyde in good yield.</description><subject>Amino acids</subject><subject>Ammonium nitrate</subject><subject>Antibiotics</subject><subject>Chromatography</subject><subject>Natural products</subject><subject>Quinone</subject><subject>Synthesis</subject><issn>2090-0112</issn><issn>2090-0104</issn><issn>2090-0112</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkU1v1DAQhiMEolXpiTuKxAWB0nocO7EvSKu2tIWKD1HOlhM7u64Su9ibwvbXM9ss_RIS9mE89jOv9c5k2UsgewCc71MCbL-mQCU8ybYpkaQgAPTpvfNWtpvSBcHFJONSPs-2KK-JFKXczj4d2uTmPtfe5N9XfrnANOWhyz-HK9vnpyn81teht_m5xbdoTf5tdD54W8wGjPmsdSY_WTXRmfQie9bpPtndTdzJfnw4Oj84Kc6-HJ8ezM4KzWgJhSUCoKSaAZOCWa5b6CpKaglMCF0ZIypBeNVUTSuILksgxlJoSGPrCi3U5U72ftK9HJvBmtb6ZdS9uoxu0HGlgnbq4Yt3CzUPV4qhGBMlCrzZCMTwc7RpqQaXWtv32tswJgUVFwxkzStEXz9CL8IYPdpDigqB_eT0jprr3irnu4D_tmtRNWO0YgydAlJ7_6BwGzu4FnvaObx_UPBuKmhjSCna7tYjELUev1qPX03jR_rV_bbcsn-HjcDbCVg4b_Qv9x-1jxOsXXRLd2f7K1IcAGpC6E0F3ITNFXmUOFDAyj_098bO</recordid><startdate>20140101</startdate><enddate>20140101</enddate><creator>Ravi Kumar, P.</creator><creator>Behera, Manoranjan</creator><creator>Sambaiah, M.</creator><creator>Kandula, Venu</creator><creator>Payili, Nagaraju</creator><creator>Jaya Shree, A.</creator><creator>Yennam, Satyanarayana</creator><general>Hindawi Limiteds</general><general>Hindawi Publishing Corporation</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>188</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>8FE</scope><scope>8FH</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4987-0942</orcidid></search><sort><creationdate>20140101</creationdate><title>Design and Synthesis of Novel Isoxazole Tethered Quinone-Amino Acid Hybrids</title><author>Ravi Kumar, P. ; 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| source | Wiley Online Library Open Access; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection; PubMed Central Open Access |
| subjects | Amino acids Ammonium nitrate Antibiotics Chromatography Natural products Quinone Synthesis |
| title | Design and Synthesis of Novel Isoxazole Tethered Quinone-Amino Acid Hybrids |
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