The early antibiotic therapy in septic patients--milestone or sticking point?

Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the...

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Veröffentlicht in:	Critical care (London, England) England), 2014-11, Vol.18 (6), p.671-671, Article 671
Hauptverfasser:	Bernhard, Michael, Lichtenstern, Christoph, Eckmann, Christian, Weigand, Markus A
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Complications and side effects Drug resistance in microorganisms Drug Resistance, Bacterial Drug therapy Health aspects Humans Sepsis - drug therapy Time Factors Treatment Outcome
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Beschreibung
Zusammenfassung:	Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the use of broad-spectrum antimicrobial agents may be associated with induction of resistance among common pathogens.
ISSN:	1364-8535 1466-609X 1364-8535
DOI:	10.1186/s13054-014-0671-1