KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

In sub-Saharan Africans, maternal mortality is unacceptably high, with >400 deaths per 100,000 births compared with

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2015-01, Vol.112 (3), p.845-850
Hauptverfasser: Nakimuli, Annettee, Chazara, Olympe, Hiby, Susan E, Farrell, Lydia, Tukwasibwe, Stephen, Jayaraman, Jyothi, Traherne, James A, Trowsdale, John, Colucci, Francesco, Lougee, Emma, Vaughan, Robert W, Elliott, Alison M, Byamugisha, Josaphat, Kaleebu, Pontiano, Mirembe, Florence, Nemat-Gorgani, Neda, Parham, Peter, Norman, Paul J, Moffett, Ashley
Format: Artikel
Sprache:eng
Schlagworte:
Biological Sciences
Blacks - genetics
Centromere
Female
Genes
Genotype & phenotype
Humans
Immunoglobulins
Molecules
Mortality
Pre-Eclampsia - genetics
Pre-Eclampsia - prevention & control
Preeclampsia
Pregnancy
Receptors, KIR - genetics
Risk factors
Whites - genetics
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Zusammenfassung:In sub-Saharan Africans, maternal mortality is unacceptably high, with >400 deaths per 100,000 births compared with
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.1413453112