A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

Risk stratification in myeloma requires an accurate assessment of the presence of a range of molecular abnormalities including the differing IGH translocations and the recurrent copy number abnormalities that can impact clinical behavior. Currently, interphase fluorescence in situ hybridization is u...

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Veröffentlicht in:	Genes chromosomes & cancer 2015-02, Vol.54 (2), p.91-98
Hauptverfasser:	Boyle, Eileen M., Proszek, Paula Z., Kaiser, Martin F., Begum, Dil, Dahir, Nasrin, Savola, Suvi, Wardell, Christopher P., Leleu, Xavier, Ross, Fiona M., Chiecchio, Laura, Cook, Gordon, Drayson, Mark T., Owen, Richard G., Ashcroft, John M., Jackson, Graham H., Anthony Child, James, Davies, Faith E., Walker, Brian A., Morgan, Gareth J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Early Detection of Cancer - methods Female Humans In Situ Hybridization, Fluorescence Male Middle Aged Multiple Myeloma - diagnosis Multiple Myeloma - genetics Multiplex Polymerase Chain Reaction Predictive Value of Tests
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