Striatal circuits, habits, and implications for obsessive–compulsive disorder

Striatal circuits, habits, and implications for obsessive–compulsive disorder

Highlights • Involvement of corticostriatal circuits in OCD is receiving strong new experimental support. • This evidence is concordant with clinical evidence based on OCD patient studies. • Clinical and experimental work further converge on OFC-ACC corticostriatal circuits as critical.

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Bibliographische Detailangaben
Veröffentlicht in:Current opinion in neurobiology 2015-02, Vol.30, p.59-65
Hauptverfasser: Burguière, Eric, Monteiro, Patricia, Mallet, Luc, Feng, Guoping, Graybiel, Ann M
Format: Artikel
Sprache:eng
Schlagworte:
Corpus Striatum - pathology
Habits
Humans
Life Sciences
Nerve Net - pathology
Neural Pathways - pathology
Neurology
Obsessive-Compulsive Disorder - pathology
Obsessive-Compulsive Disorder - psychology
Psychiatry
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Beschreibung
Zusammenfassung:Highlights • Involvement of corticostriatal circuits in OCD is receiving strong new experimental support. • This evidence is concordant with clinical evidence based on OCD patient studies. • Clinical and experimental work further converge on OFC-ACC corticostriatal circuits as critical.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2014.08.008