Whole-genome sequencing confirms that Burkholderia pseudomallei multilocus sequence types common to both Cambodia and Australia are due to homoplasy

Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian...

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Veröffentlicht in:	Journal of clinical microbiology 2015-01, Vol.53 (1), p.323-326
Hauptverfasser:	De Smet, Birgit, Sarovich, Derek S, Price, Erin P, Mayo, Mark, Theobald, Vanessa, Kham, Chun, Heng, Seiha, Thong, Phe, Holden, Matthew T G, Parkhill, Julian, Peacock, Sharon J, Spratt, Brian G, Jacobs, Jan A, Vandamme, Peter, Currie, Bart J
Format:	Artikel
Sprache:	eng
Schlagworte:	Australia Bacterial Typing Techniques Burkholderia pseudomallei Burkholderia pseudomallei - genetics Cambodia Epidemiology Evolution, Molecular Genome, Bacterial - genetics Humans Melioidosis - microbiology Multilocus Sequence Typing Phylogeny
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Zusammenfassung:	Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy.
ISSN:	0095-1137 1098-660X
DOI:	10.1128/JCM.02574-14