Sarcomatoid combined hepatocellular-cholangiocarcinoma: a case report and review of literature

Sarcomatoid combined hepatocellular-cholangiocarcinoma is an extremely rare primary hepatic malignancy and only a few cases have been reported. Herein, we report a case of combined hepatocellular-cholangiocarcinoma with sarcomatoid changes in a 52-year-old man, who had a history of liver cirrhosis a...

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Veröffentlicht in:	International journal of clinical and experimental pathology 2014-01, Vol.7 (11), p.8290-8294
Hauptverfasser:	Chin, Susie, Kim, Zisun
Format:	Artikel
Sprache:	eng
Schlagworte:	Bile Duct Neoplasms - pathology Bile Ducts, Intrahepatic - pathology Carcinoma, Hepatocellular - pathology Case Report Cholangiocarcinoma - pathology Humans Liver Neoplasms - pathology Male Middle Aged Neoplasms, Complex and Mixed - pathology Neoplasms, Second Primary - pathology
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Zusammenfassung:	Sarcomatoid combined hepatocellular-cholangiocarcinoma is an extremely rare primary hepatic malignancy and only a few cases have been reported. Herein, we report a case of combined hepatocellular-cholangiocarcinoma with sarcomatoid changes in a 52-year-old man, who had a history of liver cirrhosis and transarterial chemoembolization. The resected liver revealed a mass of 4.5×3.5 cm. Microscopically, the tumor was composed of adenocarcinoma intermingled with poorly differentiated hepatocellular carcinoma, which contained atypical spindle cells. We also present a short review of reported cases of sarcomatoid combined hepatocellular-cholangiocarcinoma.
ISSN:	1936-2625