DRD4 and susceptibility to peer influence on alcohol use from adolescence to adulthood

DRD4 and susceptibility to peer influence on alcohol use from adolescence to adulthood

Highlights • Alcohol use in early 30's was related to previous and current friends’ alcohol use only among carriers of the DRD4 long allele. • Friends’ drinking in adolescence predicted more alcohol use and heavy drinking in emerging adulthood regardless of DRD4 genotype. • Through adolescence...

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Veröffentlicht in:Drug and alcohol dependence 2014-12, Vol.145, p.168-173
Hauptverfasser: Mrug, Sylvie, Windle, Michael
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adolescents
Adult
Alcohol Abuse
Alcohol Drinking - epidemiology
Alcohol Drinking - genetics
Alcohol Drinking - psychology
Alcohol use
Alleles
DRD4
Drunkenness
Female
Females
Friends - psychology
Friendship
G × E interaction
Gene by environment
Humans
Intervention
Male
Peer
Peer Group
Peers
Psychiatry
Receptors, Dopamine D4 - genetics
Risk
Whites
Young Adult
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Beschreibung
Zusammenfassung:Highlights • Alcohol use in early 30's was related to previous and current friends’ alcohol use only among carriers of the DRD4 long allele. • Friends’ drinking in adolescence predicted more alcohol use and heavy drinking in emerging adulthood regardless of DRD4 genotype. • Through adolescence and adulthood, alcohol use and/or heavy drinking predicted having more heavily drinking friends at later time points regardless of DRD4 genotype.
ISSN:0376-8716
1879-0046
DOI:10.1016/j.drugalcdep.2014.10.009